成果论著

48. Zhang LY, Zhang K, Zhao X, Tao HP, Jia GX, Fang YG, Yang QE*. Fetal hypoxia exposure induces Hif1a activation and autophagy in adult ovary granulosa cells. Biology of Reproduction. 2024 Oct 3: ioae141. 

47. Wan RD, Gao X, Wang GW,  Wu SX, Yang QL, Zhang YW, Yang QE*. Identification of candidate genes related to hybrid sterility by genomic strucutural viariation and transcriptome analyses in cattle-yak. Journal of Dairy Science. 2024 Oct 14: S0022-0302(24)01212-8. 

45. Zhao C, Wang D, Yang C, Chen Y, Teng J, Zhang X, Cao Z, Wei X, Ning C, Yang QE*, Lv WF*, Zhang Q*. Population structure and breed identification of Chinese indigenous sheep breeds using whole genome SNPs and InDels. Genetics Selection Evolution. 2024:56,60.

44. Pan B, Qin J, Du K, Zhang L, Jia G, Ye J, Liang Q, Yang QE*, Zhou GB*. Integrated ultrasensitive metabolomics and single-cell transcriptomics identify crucial regulators of sheep oocyte maturation and early embryo development in vitro. Journal of Advanced Research. 2024: S2090-1232.

43. Wang FC, Zhang XN, Wu SX, He Z, Zhang LY, Yang QE*. Loss of PBX1 function in Leydig cells causes testicular dysgenesis and sterility. Cellular and Molecular Life Sciences. 2024;81(1):212.

42. Zhang YW, Wu SX, Wang GW, Wan RD, Yang QE*. Single-cell analysis identifies critical regulators of spermatogonial development and differentiation in cattle-yak bulls. Journal of Dairy Science. 2024;107(9):7317-7336.

41. Li S, Yan RG, Gao X, He Z, Wu SX, Wang YJ, Zhang YW, Tao HP, Zhang XN, Jia GX, Yang QE*. Single-cell transcriptome analyses reveal critical regulators of spermatogonial stem cell fate transitions. BMC Genomics. 2024; 25(1):138.

40. He Z, Yan RG, Shang QB, Yang QE*. Elevated Id2 expression causes defective meiosis and spermatogenesis in mice. Developmental Dynamics. 2023, 12(8):1-13.

39. Yan RG, He Z, Wang FC, Li S, Shang QB, Yang QE*. Transcription Factor E4F1 dictates spermatogonial stem cell fate decisions by regulating mitochondrial functions and cell cycle progression. Cell & Bioscience. 2023;13:177.

38. Jia GX, Ma WJ, Wu ZB, Li S, Zhang XQ, He Z, Wu SX, Tao HP, Fang Y, Song YW, Xu SR, Wang XQ*, Yang QE*. Single-cell transcriptomic characterization of sheep conceptus elongation and implantation. Cell Reports. 2023; 42(8):12860.

37. Tao HP, Lu TF, Li  S, Zhang XN, Jia GX, Yang QE*, Hou YP*. Pancreatic lipase-related protein 2 is selectively expressed by peritubular myoid cells in the murine testis and sustains long-term spermatogenesis. Cellular and Molecular Life Sciences. 2023;80(8):217.

36. Wu SX, Wan RD, Wang GW, Zhang YW, Yang QE*. Comparative proteomic analysis identifies differentially expressed proteins associated with meiotic arrest in cattley-yak hybrids. Proteomics. 2023; e2300107.

35. Wu SX, Wang GW, Fang YG ,Chen YW, Jin YY, Liu XT, Jia GX, Yang QE*. Transcriptome Analysis Reveals Dysregulated Gene Expression Networks in Sertoli cells of Cattle-yak Hybrids. Theriogenology. 2023;203:33-41.

34. Zhao SS, Wu SX, Jia GX, Abulizi W*, Yang QE*. Localizaiton and Expression of SLX4 in the Testis of Sterile Male Cattle-Yak. Reproduction in Domestic Animals. 2023; 3(7):14338.

33. Wang YJ, Li S, Tao HP, Zhang XN, Fang YG, Yang QE*. Arhgfe15 is expressed in undifferentiated spermatogonia but is not required for spermatogenesis in mice. Reproductive Biology. 2023; 3(1):100727.

32. Zhang XN, Tao HP, Li S, Wang YJ, Wu SX, Pan B, Yang QE*. Ldha-Dependent Metabolic Programs in Sertoli Cells Regulate Spermiogenesis in Mouse Testis. Biology. 2022;11(12):1791.

31. Gao X, Wang S, Wang YF, Li S, Wu SX, Yan RG, Zhang YW, Wan RD, He Z, Song RD, Zhao XQ*, Wu DD*, Yang QE*. Long read genome assemblies complemented by single cell RNA-sequencing reveal genetic and cellular mechanisms underlying the adaptive evolution of Yak. Nature Communications. 2022；13(1):4887.

30. Li S and Yang QE*. Hypobaric hypoxia exposure alters transcriptome in mouse testis and impairs spermatogenesis in offspring. Gene. 2022；823:164390.

29. Tao HP, Jia GX, Zhang XN, Wang YJ, Li BY, Yang QE*. Paternal hypoxia exposure impairs fertilization process and preimplantation embryo development. Zygote. 2022; 30(1):48-56.

28. Li LL, Ma SK, Peng W, Fang YG, Duo HR, Fu HY, Jia GX*. Genetic diversity and population structure of Tibetan sheep breeds determined by whole genome resequencing. Tropic Animal Health and Production. 2021; 53(1):174.

27. Jia GX, Lin Z, Yan RG, Wang GW, Zhang XN, Li C, Tong MH, Yang QE*. Wtap function in Sertoli cells is essential for sustaining spermatogonial stem cell niche. Stem Cell Reports. 2020; 15(4):968-982.

26. Yan RG, Li BY, Yang QE*. Function and transcriptomic dynamics of Sertoli cells during prospermatogonia development in mouse testis. Reproductive Biology. 2020:S1642-431X(20)30273-4.

25. Yan RG, Yang QL, Yang QE*. E4 Transcription Factor 1 (E4F1) Regulates Sertoli Cell Proliferation and Fertility in Mice. Animals. 2020; 10(9):E1691.

24. Xu SR, Peng W, Yang QL, Jia GX, Ma SK, Yang QE, Zhang J*, Zhang RN*. Transcriptome analysis revealed key signlaing networks regulating ovarian activities in the domestic yak. Theriogenology. 2020; 147:50-56.

23. Li YC, Wang GW, Xu SR, Zhang XN, Yang QE*. The expression of histone methyltransferases and distribution of selected histone methylations in testes of yak and cattle-yak hybrid. Theriogenology. 2020;144: 164-173.

22. He Z, Yan RG, Zhang XN, Yang QE*. Ring 1 and YY1 Binding Protein Is Expressed in Murine Spermatocytes but Dispensable for Spermatogenesis. Genes. 2020; 11(1).

21. Wang GW, Li YC, Yang QL, Xu SR, Ma SK, Yan RG, Jia GX, Ai DQ, Yang QE*. Gene expression dynamics during the gonocyte to spermatogonia transition in the domestic yak. Journal of Animal Science & Biotechnology. 2019; 10:64.

20. Wang YJ, Jia GX, Yan RG, Guo SC, Tian F, Ma J, Zhang RN, Li C, Zhang LZ, Du YR*, Yang QE*. Testosterone-retinoic acid signaling directs spermatogonial differentiation and seasonal spermatogenesis in the Plateau pika. Theriogenology. 2019; 125:74-82.

19. Zhang RN, Pang B，Xu SR，Wan PC，Guo SC，Ji HZ, Jia GX, Hu LY, Zhao XQ*, Yang QE*. The CXCL12-CXCR4 signaling promotes oocyte maturation by regulating cumulus expansion in sheep. Theriogenology. 2018; 107:85-94.

18. Helsel AR#, Yang QE#, Oatley MJ, Lord T, Sablitzky F, Oatley JM*. ID4 levels dictate the stem cell state in mouse spermatogonia. Development. 2017; 144(4):624-634.

17. Yang QE, Ozawa M, Zhang K, Johnson SE, Ealy AD*. The requirement for protein kinase C delta (PRKCD) during preimplantation bovine embryo development. Reproduction Fertility and Development. 2016; 28(4):482-90.(Cover Article)

16. Yang QE, Nagaoka SI, Gwost I, Hunt PA, Oatley JM*. Inactivation of Retinoblastoma Protein (Rb1) in the Oocyte: Evidence That Dysregulated Follicle Growth Drives Ovarian Teratoma Formation in Mice. PLoS Genetics. 2015; 11(7):e1005355.

15. Oatley MJ, Kaucher AV, Yang QE, Waqas MS, Oatley JM. Conditions for Long-Term Culture of Cattle Undifferentiated Spermatogonia. Biology of Reproduction. 2016 Jul; 95(1):14. 

14. Chan F, Oatley MJ, Kaucher AV, Yang QE, Bieberich CJ, Shashikant CS, Oatley JM. Functional and molecular features of the Id4+ germline stem cell population in mouse testes. Genes & Development. 2014; 28(12):1351-62.

13. Tong MH, Yang QE, Davis JC, Griswold MD. Retinol dehydrogenase 10 is indispensible for spermatogenesis in juvenile males. PNAS. 2013; 110(2):543-8.

12. Yang QE, Kim D, Kuacher A, Oatley MJ, Oatley JM*. CXCL12/CXCR4 signaling is essential for the maintenance of mouse spermatogonial stem cells. Journal of Cell Science. 2013; 15;126:1009-20.

11. Yang QE, Gwost I, Oatley MJ, Oatley JM*. Retinoblastoma Protein (RB1) controls fate determination in stem cells and progenitors of the mouse male germline. Biology of Reproduction. 2013; 89 (5):113.

10. Yang QE and Oatley JM. Spermatogonial stem cell functions in physiological and pathological conditions. Current Topics in Developmental Biology. 2014,107: 235-267.

09. Yang QE#, Racicot K#, Kaucher A#, Oatley MJ, Oatley JM*. MicroRNAs 221 and 222 regulate the undifferentiated state in mammalian male germ cells. Development. 2013; 140 (2):280-290.

08. Ozawa M, Yang QE, Ealy AD*. The expression of fibroblast growth factor receptors during early bovine conceptus development and pharmacological analysis of their actions on trophoblast growth in vitro. Reproduction. 2013; 1458(2):191-201.

07. Yang QE, Giassetti MI, Ealy AD*. Fibroblast growth factors activate mitogen-activated protein kinase pathways to promote migration in ovine trophoblast cells. Reproduction. 2011: 141(5):707-714.

06. Yang QE, Johnson SE, Ealy AD*. Protein kinase C delta mediates fibroblast growth factor- 2-induced interferon-tau expression in bovine trophoblast. Biology of Reproduction. 2011: 84(5):933-43.

05. Yang QE, Fields SD, Zhang K, Ozawa M, Johnson SE, Ealy AD*. Fibroblast growth factor 2 promotes primitive endoderm development in bovine blastocyst outgrowths. Biology of Reproduction. 2011: 85(5):946-53.

04. Ealy AD*, Yang QE. Control of interferon-tau expression duirng early pregnancy in ruminants. Am J of Reproductive Immunology. 2009; 61(2):95-106.

03. Yan CL#, Yang QE#, Zhou GB, Hou YP, Zhao XM, Fan ZQ, Liu MQ, Liu L, Zhu SE*. Open-pulled straw (OPS) vitrification of in vitro fertilised mouse embryos at various stages. Acta Veterinaria Hungarica. 2008; 56(2):245-53.

02. Yang QE, Hou YP, Zhou GB, Yang ZQ, Zhu SE*. Stepwise in-straw dilution and direct transfer using open pulled straws (OPS) in the mouse: a potentail model for field manipulaiton of vitrified embryos. Journal of Reproduction & Development. 2007；53(2):2115.

01. Yang QE and Oatley JM. Eearly Interactions between Germ cells and Sertoli cells. Sertoli Cell Biology. Chapter 3，Edited by MD Griswold，2014

安晓宇，王玉军，李永昌，贾功雪，杨其恩*. 高原鼢鼠精子发生的形态学特征和关键调控因子探究. 兽类学报，2020；40(5):435-445.

贾功雪, 丁路明，徐尚荣，方有贵，付弘赟，杨其恩*. 青藏高原牦牛遗传资源保护和利用：问题与展望. 生态学报，2020；40(18):6314-6323

李双，贾功雪，陶海萍，王玉军，李斌业，杨其恩*. 低压低氧对小鼠精子发生及其小RNA表达的影响. 兽类学报，2022, 42(5):579-589. 

陶海萍，李双，贾功雪，张璐瑶，方有贵，陈永伟，杨其恩*. 高原低氧胁迫对小鼠肝脏功能及基因表达的影响. 兽类学报，2022；42(05):590-600.

王玉军, 张晓茜, 方有贵, 杨其恩*, 贾功雪*. 高原鼠兔发情周期性激素与性器官变化特征. 兽类学报. 2024, 44(3): 351-359.

方有贵, 薛生华, 张玉海, 马春兰, 赵海霞, 叁旦卓玛, 周毛, 贾功雪, 张科, 张璐瑶, 杨其恩*.  玛多羊种质资源特性及保护利用. 中国畜禽种业. 2024, 20 (4): 133-143.

参编著作

朱士恩主编, 杨其恩等参编,《动物配子与胚胎冷冻保存原理与应用》, 科学出版社 ，2016.

艾德强 周伯成 杨其恩主编,《青海牦牛》, 青海民族出版社, 2022. 

科技成果

艾德强; 官却扎西；拉环；马进寿；晓虎；达哇；付弘赟；拉毛多杰；周伯成；宋仁德；杨其恩等. 扎什加羊，2019.